Comedy / Science Fiction /

Score: 62.3%( 445 votes )

Overview: A brain surgeon marries a femme fatale, causing his life to turn upside down. Things go more awry when he falls in love with a talking brain.

Cast:

Steve Martin
Dr. Michael Hfuhruhurr

Kathleen Turner
Dolores Benedict

David Warner
Dr. Alfred Necessiter

Paul Benedict
Butler

Richard Brestoff
Dr. Pasteur

James Cromwell
Realtor

George Furth
Timon

Peter Hobbs
Dr. Brandon

Earl Boen
Dr. Felix Conrad

Bernie Hern
Gun Seller

Francis X. McCarthy
Olsen

William Traylor
Inspector

Randi Brooks
Fran

Bernard Behrens
James Gladstone

Natividad Vacío
Ramon

David Byrd
Desk Clerk

Adrian Ricard
Nurse in Room

Sparky Marcus
Bellboy

Perla Walter
Housekeeper

Mya Stark
Little Girl

Don McLeod
Dr. Schlermie Beckerman / Gorilla

Peter Elbling
Morgue Attendant

Kate Sarchet
Hooker #2

Wendy Sherman
Hooker #3

Tom Spratley
Minister

Estelle Reiner
Tourist in Elevator

Jeffrey Combs
Dr. Jones

Jenny Gago
Nurse #1

Haunani Minn
Nurse Breen

Stepfanie Kramer
Beautiful Girl Hit by Car

George Fisher
Patrol Car Officer

Merv Griffin
The Elevator Killer

Bob Harks
Lecture Guest (uncredited)

Sissy Spacek
Anne Uumellmahaye (uncredited) (voice)